Daughter of Mexican immigrants Ms Perez was born in Chicago.
She won various prestigious awards before making her debut as Juliette in Romeo and Juliette alongside Rolando Villazón in 2008 in Salzburg.
One of her signature roles is Violetta in La Traviata, which she has performed at Deutsche Staatsoper Berlin, Hamburg State Opera, Vienna Staatsoper and The Royal Opera House. She has also sung Amelia alongside Plácido Domingo in Simon Boccanegra at the Deutsche Staatsoper and it was her debut role at La Scala.
In 2010 she appeared as Mimì in La Bohème at Cincinnati Opera. Her repertory includes roles such as the Countess and Susanna in Le Nozze di Figaro, Adina in L'elisir d'amore, Zerlina in Don Giovanni, Pamina and Papagena in Die Zauberflote, and Marguerite in Faust.
Ms Perez enjoys growing recognition and is married to tenor Stephen Costello.